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目的:探讨额骨孤立浆细胞瘤(SPB)的影像学特征及诊断方法。方法:回顾性分析重庆市江津区中心医院和大足区人民医院经病理确诊的额骨SPB 7例,经过临床资料、影像学表现、血尿化验、病理切片及免疫组化染色等进行观察分析。结果:7例SPB影像学表现:1均位于大脑中线部位;2单发,病变范围>5 cm;3位于颅骨内外板之间,周围无骨质增生硬化及骨膜反应;4骨破坏区仍可辨原始骨板的轮廓;5与脑实质边界清楚,可见“假包膜”样表现;6周围的脑实质无水肿;7增强扫描病灶明显强化;8邻近的板障强化;9大脑实质受压,出现特征性的“脑回样压迹征”。免疫组化为:CD 138(+),CD 38(+),Mu M-1(+),CD 20(-),ki 67 10%(+)。结论:颅骨SPB的影像学特征有助于正确、早期诊断颅骨的SPB。
Objective: To investigate the imaging features and diagnosis of frontal solitary plasmacytoma (SPB). Methods: Seven cases of pathologically diagnosed frontal bone SPB in Jiangjin Central Hospital and Dazu District People’s Hospital were retrospectively analyzed. The clinical data, imaging findings, blood and urine tests, pathological sections and immunohistochemical staining were observed and analyzed. Results: 7 cases of SPB imaging findings: 1 are located in the midline of the brain; 2 single, the lesion range> 5 cm; 3 in the skull between the outer and outer plates without bone hyperplasia and periosteal reaction; 4 bone destruction area can still Identify the outline of the original plate; 5 and the brain parenchyma clear, visible “pseudocapsule” -like performance; 6 around the parenchyma no edema; 7 enhanced scan lesions significantly enhanced; 8 adjacent plate strengthening; 9 brain parenchyma Pressure, there characteristic “brain back sample pressure sign”. Immunohistochemistry was: CD 138 (+), CD 38 (+), Mu M-1 (+), CD 20 (-), ki 67 10% (+). Conclusion: The imaging features of skull SPB are helpful to correct and early diagnosis of skull SPB.