Partition of Chiral pharmaceutical intermediate R（-）-Mandelic Acid in Aqueous Two-Phase System of Po

• 作 者: XuXiaoping LiZhongqin ChenJieb
• 机 构: DepartmentofChemicalEngineeringFuzhouUniversity
• 出 处: 中国新医药
• 发表日期: 2004年1期
• 关键词: 苦杏仁酸 水二相聚乙烯系统 铵硫酸盐 手性药物 药物媒介

An aqueous two-phase system of poly (ethylene glycol)-ammonium sulfate was employed to separate R (-)-mandelic acid. The result showed that R (-)-mandelic acid has priority to partition in PEG-rich top phase. This indicated that aqueous two-phase is a ver