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目的:考察路盖克(每片含双氢可待因酒石酸盐10mg和醋氨酚500mg)用于骨科术后及非手术疾患的镇痛效果和不良反应。方法:108例开放试验,po,2片/次,qd给药。结果:完全缓解者为60例,占受试者总数的5556%,明显缓解者为27例,占2500%;中度缓解者为5例,占463%;轻度缓解者为13例,占1204%;未缓解者为3例,占278%。中度以上疼痛缓解率为8519%,总有效率为9723%。服药30分钟后出现嗜睡6例,恶心2例,心慌、乏力、头痛各1例。这些副作用持续时间短,不需特珠处理,可自行缓解。结论:路盖克对术前、术后的骨科疾患有良好的镇痛效果,起效快,持续时间长,不良反应小,具有良好的安全性
OBJECTIVE: To investigate the analgesic effect and side effects of Lucchik (each tablet containing 10 mg of dihydrocodeine tartrate and 500 mg of acetaminophen) for orthopedic and non-surgical disorders. Methods: 108 open trials, po, 2 tablets / time, qd administration. Results: The complete remission was 60 cases, accounting for 5556% of the total number of subjects, 27 cases were significantly relieved, accounting for 2500%; 5 cases of moderate remission, accounting for 463%; mild remission Among them, 13 cases accounted for 12.04%, 3 cases were unreacted, accounting for 278%. Moderate pain relief rate was 85.19%, the total effective rate was 97 23%. Drowsiness occurred in 6 cases 30 minutes after taking the medication, nausea in 2 cases, palpitation, fatigue, headache in 1 case. Short duration of these side effects, without special bead treatment, self-remission. Conclusion: Luk grams on the preoperative and postoperative orthopedic disorders have a good analgesic effect, rapid onset, long duration, small adverse reactions, with good safety