论文部分内容阅读
用聚合酶链反应（ＰＣＲ）技术检测１１０例早孕妇女尿液及其胚胎绒毛的ＨＣＭＶＤＮＡ。结果孕母尿液与胚胎绒毛的ＨＣＭｖＤＮＡ阳性率分别为１５．５％和７．３％，宫内感染率为４ｌ２％，孕母尿液与胚胎绒毛的ＨＣＭＶ阳性数密切相关（Ｐ＜０．０１），提示孕母尿路排毒系全身性活动性感染；孕母尿液ＨＣＭＶ阳性与阴性者其胚胎绒毛ＨＣＭＶ阳性数具显著差异（Ｐ＜０．０１），表明孕母尿液阳性者较阴性者处于垂直感染胚胎的高危状态，建议采用ＰＣＲ法普查早孕妇女尿液ＨＣＭＶＤＮＡ，并对阳性者严密监视胎儿发育情况，酌情采取相应措施。
Polymerase chain reaction (PCR) was used to detect HCMVDNA in urine and embryos of 110 early pregnant women. Results The positive rates of HCMvDNA in urine of pregnant women and embryos were 15.5% and 7.3%, respectively. The intrauterine infection rate was 4l2%. The positive numbers of HCMV in pregnant women ’s urine and embryo villi were closely related (P <0. 01), suggesting that pregnant women urinary detoxification system systemic infection; pregnant women urine HCMV positive and negative embryos villi HCMV positive numbers were significantly different (P <0.01), indicating that pregnant women with positive urine were more Negatives are at a high risk of vertically infected embryos. It is recommended to use PCR to screen urine HCMVDNA in early pregnant women, and closely monitor fetal development in positive cases, and take relevant measures as appropriate.