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目的观测自体骨髓注射治疗单纯性骨囊肿的影像学改变,分析其临床意义。方法自体骨髓注射治疗单纯性骨囊肿患儿27例,获随访25例,随访平均3．3年。以CR摄影判定影像学上的疗效;观测术后不同时期X线骨囊肿面积、皮质厚度的变化情况;分术前合并病理骨折组及无病理骨折组,测算术前囊肿纵径／最小皮质厚度,行组间比较。通过三维CT结合X线观察骨囊肿的基本愈合形式。结果1次注射后愈合10例,缺损愈合5例,持续存在7例(含2例无反应),复发3例。除外无反应者,术后3个月病灶内均有不同程度的密度增高;X线骨囊肿面积基本稳定,主要发生在术后6-9个月(21／23);X线骨囊肿皮质厚度基本稳定,主要发生在术后9个月-1年(19／23)。除外下肢持重管状骨病变,术前合并病理骨折组及无病理骨折组囊肿纵径与最小皮质厚度比值差异显著。结论自体骨髓注射治疗单纯性骨囊肿术后随访至少1年;该法通过骨皮质增厚,囊腔内骨嵴及骨小梁向心性增生,分割包绕填塞囊腔而逐步愈合。
Objective To observe the imaging changes of simple bone cysts injected with autologous bone marrow and analyze its clinical significance. Methods Twenty-seven children with simple bone cyst were injected with autologous bone marrow, and 25 patients were followed up for an average of 3.3 years. To determine the imaging effect of CR photography; observe the changes of X-ray bone cyst area and cortical thickness at different stages after surgery; preoperatively combined with pathological fracture group and non-pathological fracture group, the longitudinal diameter / minimum cortical thickness Line group comparison. Three-dimensional CT combined with X-ray observation of the basic form of bone cyst healing. Results After one injection, 10 cases were healed, 5 cases were defect healing, 7 cases persisted (including 2 cases without response) and 3 cases relapsed. Except non-responders, the density of the lesion increased in varying degrees within 3 months after operation. The area of X-ray cyst was basically stable, mainly occurring at 6-9 months (21/23) after surgery. The thickness of X-ray cyst Basically stable, mainly occurred in 9 months after operation - 1 year (19/23). Except for the lower extremity weight-bearing tubular bone lesions, preoperative pathological fracture group and non-pathological fracture group cyst longitudinal diameter and minimum cortical thickness ratio was significantly different. Conclusion Autologous bone marrow injection for the treatment of simple bone cysts was followed up for at least 1 year. This method was gradually cortical healed by cortical bone thickening, bone crest and trabeculae in the cystic cavity.