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目的探讨血清降钙素原(PCT)和C-反应蛋白(CRP)联合检测在感染性疾病诊断中的应用。方法将160例西华县人民医院收治的感染性疾病患者分为细菌感染组95例、非细菌感染组65例,另选本院健康体检者50例为对照组,分别检测各组研究对象血清中PCT和CRP水平。结果与非细菌感染组和对照组比较,细菌感染组患者血清平均PCT和CRP水平和阳性率均显著升高(P<0.05);细菌感染组患者在感染得到控制后,其血清PCT和CRP水平迅速回落至正常水平。结论血清PCT、CRP可用于感染性疾病的诊断和鉴别诊断,动态监测血清PCT和CRP水平变化可及时了解患者的病情变化,为提高疗效及调整抗生素药物应用提供依据。
Objective To investigate the combination of serum procalcitonin (PCT) and C-reactive protein (CRP) in the diagnosis of infectious diseases. Methods One hundred and sixty cases of infectious diseases admitted to Xihua County People’s Hospital were divided into bacterial infection group (n = 95), non-bacterial infection group (n = 65), and the other 50 healthy subjects were selected as control group. Serum PCT and CRP levels. Results Compared with non-bacterial infection group and control group, serum PCT and CRP levels and positive rates in bacterial infection group were significantly increased (P <0.05). After infection was controlled, the serum PCT and CRP levels Quickly fell back to normal levels. Conclusions Serum PCT and CRP can be used in the diagnosis and differential diagnosis of infectious diseases. Dynamic changes in serum PCT and CRP levels can be monitored in time to understand the changes of patients’ condition, and provide the basis for improving the curative effect and adjusting the application of antibiotics.