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目的评价９９Ｔｃｍ甲氧基异丁基异腈（ＭＩＢＩ）双时相显像法在肾性继发性甲状旁腺功能亢进（ＳＨＰ）患者中的诊断价值。方法２０例因慢性肾功能衰竭行血液透析患者，临床诊断为ＳＨＰ，均行双时相法９９ＴｃｍＭＩＢＩ甲状旁腺显像。运用甲状旁腺／甲状腺（ＰＴ／Ｔ）比值及甲状旁腺指数（ＰＴＩ）观察阳性病灶对ＭＩＢＩ的清除。３例行颈部探查术并作甲状旁腺自体移植。结果８例显像阳性，其中３例手术摘除９枚甲状旁腺，均经病理证实为增生。９９ＴｃｍＭＩＢＩ显像发现其中的８枚，其灵敏度为８８９％。在透析年限长、甲状旁腺素分泌高的患者中，有更高的阳性率。发现有３种ＭＩＢＩ清除类型。结论９９ＴｃｍＭＩＢＩ双时相显像在ＳＨＰ患者中有较高的定位诊断价值。阅片时应考虑病灶清除ＭＩＢＩ的多样性，以免漏诊
Objective To evaluate the diagnostic value of 99Tcm-methoxyisobutylisonitrile (MIBI) dual-phase imaging in patients with secondary renal hyperparathyroidism (SHP). Methods 20 cases of hemodialysis patients with chronic renal failure, clinical diagnosis of SHP, both double-phase 99TcmMIBI parathyroid imaging. The removal of MIBI from the positive lesions was observed using the ratio of parathyroid / thyroid (PT / T) and parathyroid index (PTI). 3 cases of neck exploration and parathyroid autotransplantation. Results 8 cases were positive imaging, including 3 cases of surgical removal of parathyroid in 3 cases, all confirmed by the pathology of hyperplasia. Eight of them were found by 99Tcm-MIBI imaging, with a sensitivity of 88.9%. In patients with long dialysis, high parathyroid hormone secretion in patients with a higher positive rate. There are 3 types of MIBI clearance found. Conclusion 99TcmMIBI dual-phase imaging in patients with SHP has a higher localization of diagnostic value. Reading film should be considered to clear the diversity of MIBI lesions, so as to avoid misdiagnosis