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自1962年使用乙胺丁醇及其后以利福平加强疗效以来,开始了化疗的新时期,目前肺结核病的最佳疗法应根据以下原则:(1)在家中治疗,(2)尽快恢复正常工作,(3)使用最好的药物(异烟肼INH,乙胺丁醇EMB和利福平RFP),(4)短程化疗,(5)缩短随访时间。基于以上设想,自1972年4月起,对一组病人进行了治疗。病人均为痰菌阳性的肺结核初治病例,是否耐药菌不论。病人均不住院,大多数继续原来的工作,伴有发热,咯血等症状者停止工作数日或数周。符合上述条件并完成了疗程的共136例,其中男性90人,女性46人。15~30岁89人,31~45岁40人,46~60岁7人。根据胸片病变程度分组为轻度6例,中度36例,重度94例。有6例伴有肺外结核,15例有合并
Since the introduction of ethambutol in 1962 and subsequent treatment with rifampicin to enhance efficacy, the new era of chemotherapy is beginning and the current best treatment for tuberculosis should be based on the following principles: (1) treatment at home, (2) recovery as soon as possible Work properly, (3) use the best drugs (isoniazid INH, ethambutol EMB and rifampin RFP), (4) short-course chemotherapy, and (5) shorten the follow-up time. Based on the above assumptions, a group of patients were treated since April 1972. Patients are sputum positive tuberculosis initial cases, whether resistant bacteria. Patients were not hospitalized, most continue their original work, accompanied by fever, hemoptysis and other symptoms stop working for days or weeks. In line with the above conditions and completed a total of 136 cases of treatment, of which 90 were males, 46 females. 89 to 15 years old, 40 to 31 to 45 years old, 7 to 46 years old. According to the degree of chest lesions were classified as mild in 6 cases, moderate in 36 cases, severe in 94 cases. There are 6 cases with extrapulmonary tuberculosis, 15 cases were merged