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目的探讨阿托伐他汀联合曲美他嗪治疗冠心病的临床效果。方法收集2013年8月至2016年9月收治的86例冠心病患者,根据治疗药物的不同随机分为实验组和对照组各43例,两组在常规治疗的基础上实验组患者应用阿托伐他汀联合曲美他嗪治疗,对照组患者给予阿托伐他汀治疗,比较两组患者治疗效果、心绞痛发作次数及时间、不良反应情况等。结果实验组患者总有效率为97.67%,明显高于对照组的79.06%,差异具有具有统计学意义(P<0.05)。实验组心绞痛发作次数明显下降,发作时间缩短,差异具有统计学意义(P<0.05),两组不良反应发生情况比较差异无统计学意义(P>0.05)。结论冠心病患者应用阿托伐他汀联合曲美他嗪治疗可明显提高治疗效果,改善心绞痛,安全性高,临床值得推广应用。
Objective To investigate the clinical efficacy of atorvastatin combined with trimetazidine in the treatment of coronary heart disease. Methods Eighty-six patients with coronary heart disease who were admitted from August 2013 to September 2016 were randomly divided into experimental and control groups, 43 cases in each group. On the basis of routine treatment, In the control group, patients in the control group were given atorvastatin, and the treatment effect, the number and time of angina pectoris, adverse reactions and so on were compared between the two groups. Results The total effective rate of the experimental group was 97.67%, which was significantly higher than 79.06% of the control group, the difference was statistically significant (P <0.05). The incidence of angina pectoris in experimental group decreased significantly, the onset time shortened, the difference was statistically significant (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Atorvastatin combined with trimetazidine treatment in patients with coronary heart disease can significantly improve the treatment effect, improve angina pectoris, high safety, clinical worthy of promotion and application.