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重庆医科大学神经病学研究室董为伟等从牛脑提纯髓磷脂碱性蛋白(MBP)获得成功,并在国内首先采用ELISA法测定脑脊液的MBP抗体。共测定各种神经系统疾病367例,其中122例急性脑血管疾病中,10比脑脊液MBP抗体阳性(82.8%),他们还发现抗体水平的高低与病程早晚、病情轻重(意识障碍、偏瘫)、CT检查阳性发现及近期后优劣相一致。40例散发性脑炎患者中,38例阳性(95%),抗体水平亦与病情轻重、脑电图异常、病程早晚相一致。17例多发性硬化患者中14例阳性(82.4%),其抗体水平亦与病程、病情轻重相关。4例视神经脊髓炎中2例阳性,其平均值较对照组稍高,但无显著差别(P>0.1)。其他神经系
Department of Neurology, Chongqing Medical University, Dong Weili purification of myelin alkaline protein (MBP) was successful, and first in the country by ELISA method for the determination of cerebrospinal fluid MBP antibody. A total of 367 cases of various neurological diseases were determined. Among 122 cases of acute cerebrovascular disease, 10 were positive for CSF MBP antibody (82.8%). They also found antibody levels in the morning and evening and their severity (disturbance of consciousness, hemiparesis) CT examination of positive findings and the pros and cons of the recent agreement. Among the 40 patients with sporadic encephalitis, 38 were positive (95%). The antibody level was also consistent with the severity of the disease, abnormal EEG, and the course of the disease. Of the 17 patients with multiple sclerosis, 14 were positive (82.4%). Their antibody levels were also correlated with their duration and severity. Two cases of optic neuromyelitis were positive in 4 cases, the average value was slightly higher than that of the control group, but there was no significant difference (P> 0.1). Other nervous system