新型放射性32P-血管支架的制备

• 作 者: 张晓东 李文新 高东升 李晴暖 汪颖 李宇国 黄旋 陈润芬 黄定九
• 机 构: 中国科学院上海原子核研究所放药中心,中国科学院上海原子核研究所放药中心,上海第二医科大学附属仁济医院心内科,中国科学院上海原子核研究所放药中心,中国科学院上海原子核研究所放药中心,中国科学院上海原子核
• 出 处: 核技术
• 发表日期: 2002年01期
• 关键词: 32P 放射性支架 Ni-(32P)P化学镀 次磷酸钙

In this work a new method was described to prepare 32 P-radioactive stents which was used to reduce the restenosis after PTCA. This new method included four steps: electroplating Ni film which can catalyze the chemical plating reaction; chemical plating Ni-( 32P)P film; electroplating Au film and heat treating on 620-640℃. The second step was most important. 32 P-calcium hypophosphite was adopted as the radioactive source. 22 of 32 P-stents with the radioactivity range from 0.3 to 1.4 were achieved successfully.

This new method includes four steps: electroplating Ni film which can catalyze the chemical plating reaction; chemical plating Ni- (32P) P-calcium hypophosphite was adopted as the radioactive source. 22 of 32 P-stents with the radioactivity range from 0.3 to 1.4 were successfully.