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[目的]了解泉州市乙型病毒性肝炎流行现状,为制订防治策略提供科学依据。[方法]2006年10~12月采取分层多阶段随机抽样方法,全市分3层共抽取11个县区,22个村,4643人作为研究样本,用酶联免疫吸附试验(ELISA)检测乙肝两对半。[结果]人群各指标阳性率HBsAg为12.77%、抗-HBs为51.30%、HBeAg为3.12%、抗-HBe为7.54%、抗-HBc为34.25%,HBsAg阳性率儿童峰消失。接种乙肝疫苗人群HBsAg阳性率低于未接种者,差异有统计学意义。[结论]乙型肝炎仍然是泉州地区重要传染病,应加强对乙型肝炎的预防工作,预防乙型肝炎病毒感染最有效的措施是接种乙型肝炎疫苗。
[Objective] To understand the epidemic situation of hepatitis B in Quanzhou and provide scientific basis for formulating prevention and cure strategies. [Methods] From October to December 2006, a stratified and multi-stage random sampling method was adopted. In the whole city, 11 counties, 22 villages and 4643 people were selected as the research samples in three layers. The hepatitis B virus (HBV) was detected by enzyme linked immunosorbent assay (ELISA) Two and a half. [Results] The positive rate of each index in population was 12.77%, anti-HBs was 51.30%, HBeAg was 3.12%, anti-HBe was 7.54%, anti-HBc was 34.25%, HBsAg-positive children disappeared. The HBsAg positive rate of hepatitis B vaccination population was lower than that of non-vaccinated ones, the difference was statistically significant. [Conclusion] Hepatitis B is still an important infectious disease in Quanzhou. Hepatitis B prevention should be strengthened. The most effective measure to prevent hepatitis B virus infection is Hepatitis B vaccine.