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[目的]分析原发性闭经和继发性闭经患者的病因分布,评价闭经患者的生存质量,并探讨闭经患者生存质量的主要影响因素,为准确诊治闭经患者、改善病员生活质量提供理论依据。[方法]采用设计的问卷对2008年7~8月间在四川大学华西妇女儿童医院就诊的闭经患者进行相关调查,并用SF-36量表对调查对象进行生存质量评价。[结果]原发性闭经以下丘脑垂体病变最多,多囊卵巢综合征最少,而继发闭经多囊卵巢综合征最多见,最少的是子宫病变;闭经患者的生存质量比四川省常模低;精神压力是影响闭经患者生存质量的最主要因素。[结论]原发性闭经和继发性闭经的病因分布情况不同。在临床工作中,要关注闭经患者的生存质量,尤其是农村患者的生存质量;除了要治疗闭经患者的本身疾病,还应给予患者精神支持,减轻其精神压力,以全面提高其生存质量。
[Objective] To analyze the etiological distribution of patients with primary amenorrhea and secondary amenorrhea and to evaluate the quality of life in patients with amenorrhea and explore the main influencing factors of quality of life in patients with amenorrhea, so as to provide a theoretical basis for accurately diagnosing and treating the patients with amenorrhea and improving their quality of life. [Methods] The questionnaire was used to investigate the amenorrhea patients treated in West China Women and Children Hospital of Sichuan University from July to August in 2008, and the quality of life was evaluated with SF-36 scale. [Results] The most common lesions of hypothalamus and pituitary were observed in primary amenorrhea with the least polycystic ovary syndrome. The most common secondary polycystic ovary syndrome was secondary amenorrhea, and the least was uterine lesions. The quality of life in amenorrhea patients was lower than that in Sichuan Province. Mental stress is the most important factor affecting the quality of life of amenorrhea patients. [Conclusion] The etiological distribution of primary amenorrhea and secondary amenorrhea are different. In clinical work, we should pay attention to the quality of life of amenorrhea patients, especially the quality of life of rural patients; in addition to treatment of amenorrhea patients with their own disease, patients should also be given spiritual support to reduce the mental stress in order to fully improve their quality of life.