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[目的]观察六味地黄丸联合格列美脲治疗肝肾阴虚型糖尿病疗效。[方法]使用随机平行对照方法,将48例住院患者按就诊顺序号抽签方法简单随机分为两组。对照组27例格列美脲,1~2mg/次,1次/d,早餐时或第一次主餐时口服。治疗组21例六味地黄丸,9g/次,2次/d,早晚口服;格列美脲治疗同对照组。连续治疗2个月为1疗程。观测临床症状、血浆空腹葡萄糖、非空腹血糖、体质指数、不良反应。治疗1个疗程,判定疗效。[结果]治疗组显效18例,有效7例,无效2例,总有效率92.59%。对照组显效9例,有效8例,无效4例,总有效率80.95%。治疗组疗效优于对照组(P<0.05)。[结论]六味地黄丸联合格列美脲治疗肝肾阴虚型糖尿病,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the therapeutic effect of Liuweidihuang Pill combined with glimepiride on liver-kidney-yin deficiency type diabetes mellitus. [Methods] Using randomized parallel control method, 48 inpatients were randomly divided into two groups randomly according to the order number lottery. Control group, 27 cases of glimepiride, 1 ~ 2mg / time, 1 time / d, breakfast or the first time when the main meal orally. The treatment group, 21 cases of Liu Wei Di Huang Wan, 9g / times, 2 times / d, morning and evening oral; glimepiride treatment with the control group. Continuous treatment for 2 months as a course of treatment. Clinical symptoms, plasma fasting glucose, non-fasting blood glucose, body mass index, adverse reactions were observed. Treatment of a course of treatment to determine the efficacy. [Results] The treatment group markedly effective in 18 cases, effective in 7 cases, 2 cases, the total effective rate was 92.59%. In the control group, 9 cases were markedly effective, 8 cases were effective, 4 cases were ineffective, and the total effective rate was 80.95%. The treatment group was better than the control group (P <0.05). [Conclusion] Liuweidihuangwan combined with glimepiride in the treatment of liver - kidney - yin - deficiency type diabetes has satisfactory curative effect and no serious side effects. It is worth popularizing.