Genetic factors associated with non-motor symptoms in Parkinson’s disease

• 作 者: Yilun Ge Kai Li Chunfeng Liu
• 机 构: DepartmentofNeurologyandSuzhouClinicalResearchCenterofNeurologicalDisease,InstituteofNeuroscience
• 出 处: 转化神经科学电子杂志(英文)
• 发表日期: 2019年1期
• 关键词: Parkinson's disease (PD) NON-MOTOR SYMPTOMS (NMSs) GENETIC DIFFERENTIATION
• 基金项目: the National Key R&D Program of China (No. 2017YFC0909100),the Jiangsu Provincial Special Program of Medical Science (No. BE2018658),the Jiangsu Provincial Key R&D Program (No. BE2017653).

Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer’s disease. It is a complex syndrome with heterogeneous aetiologies, pathogenesis and manifestations. Patients with PD may present with motor symptoms and various