论文部分内容阅读
目的:用三维体表成像技术客观评估不同提纯方法(静置法、过滤法)对面部脂肪移植效果的优劣性。方法:2016年1月至2017年2月，北京大学第三医院成形外科用三维体表成像技术对47例(年龄20～50岁，平均32岁)女性面部脂肪移植患者，分为过滤组和静置组，比较两种提纯方法对脂肪移植后体积留存率的差异，了解移植脂肪组织的吸收规律。结果:过滤组术后1个月体积留存率高于静置组，术后3、6、12个月两组之间体积留存率比较，差异无统计学意义。过滤组与静置组在术后1～3个月脂肪组织吸收最快，虽然两组术后12个月也出现体积减少，但过滤组在术后3～6个月时，体积逐渐稳定，体积吸收速度明显减慢；静置组在术后6个月体积吸收速度明显减慢。结论:静置和过滤两种提纯方法对脂肪移植远期效果差异不显著，移植后脂肪组织的存活机制还需进一步研究。“,”Objective:To compare the effect of different processing methods on autologous facial fat grafting based on three-dimensional surface imaging techniques.Methods:From January 2016 to February 2017, 47 patients (all females, age: 20-50 years old, average: 32 years old) who underwent facial fat grafting were included in our prospective randomized controlled study to compare the effect on volume retention of two processing methods. The compared two processing methods were decantation and filtering. We measured the volume retention and explored the absorption rules of fat grafting over time using three-dimensional surface imaging techniques.Results:In the prospective study, the retention rate was higher in the filtering group than in the decantation group at 1 month after operation. However, there was no significant difference in the retention rate between the two groups at 3 months, 6 months and 12 months after operation. Both groups showed the fastest decrease in volume over the first 1 to 3 months. Although the volume of the two groups was reduced at 12 months after operation, the volume absorption was significantly slowed down in filtering group over 3 to 6 months after operation and 6 months after operation in decantation group.Conclusions:There is no significant difference in the long term effects of the two processing methods. There is a need for further histological analysis to compare the differences and influencing mechanisms between the two groups.