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目的:探讨米非司酮治疗子宫肌瘤疗效。方法:对子宫肌瘤50例患者采用米非司酮12.5mg自月经第1天开始服用,连服3个月为1个疗程。用药前后超声测量子宫及子宫肌瘤径线;检测雌孕激素、血红蛋白、肝肾功能、不良反应。结果:治疗期间均闭经,雌孕激素水平维持于增殖早期,血红蛋白上升,子宫及最大肌瘤的体积缩小,有统计学差异。结论:米非司酮治疗子宫肌瘤有较好的临床效果。
Objective: To investigate the efficacy of mifepristone in the treatment of uterine fibroids. Methods: 50 cases of uterine fibroids with mifepristone 12.5mg from the first day of menstruation to take, even for 3 months for a course of treatment. Uterine and uterine fibroids were measured before and after treatment Diameter; test estrogen and progesterone, hemoglobin, liver and kidney function, adverse reactions. Results: All patients were amenorrhea during the treatment period. The levels of estrogen and progesterone remained at the early stage of proliferation, the hemoglobin increased, the volume of the uterus and maximal myoma decreased, with statistical difference. Conclusion: Mifepristone treatment of uterine fibroids have a good clinical effect.