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Sjogren综合征(下称SjS)目前已引起较多重视,其原因是:1)发病率很高,据认为在胶原性疾患中仅次干类风湿性关节炎,占第二位。2)临床表现多种多样,除口、眼干燥等基本症状外,尚可侵犯胃肠、呼吸、泌尿、神经、皮肤、牯膜、淋巴、心脏、甲状腺等多种脏器或组织,属于多科性边缘性疾病,因而往往容易误诊或漏诊。3)不少胶原病常伴有涎腺、泪腺的损害,SjS也常合并胶原性疾患,互相重叠,不少情况属于重叠综合征范畴,因而其间概念常易混淆不清。但是有关SjS的诊断和分型至今尚未有统一看法,为此特收集该方面文献作一综述。
Sjogren’s syndrome (SjS) has now attracted more attention due to: 1) a high incidence of rheumatoid arthritis, which is said to be secondary only to collagen disorders. 2) A variety of clinical manifestations, in addition to mouth, dry eyes and other basic symptoms, can still infringe the gastrointestinal, respiratory, urinary, nerve, skin, membrane, lymph, heart, thyroid and other organs or tissues, It is often easily misdiagnosed or misdiagnosed as a marginal disease. 3) a lot of collagen disease often accompanied by salivary gland, lacrimal gland damage, SjS is often associated with collagen disorders, overlap each other, many cases belong to the area of overlap syndrome, so the concept is often confused. However, there is no unified opinion on the diagnosis and typing of SjS. Therefore, the literature on this topic is reviewed.