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患者,女性,50岁。10年前出现双下肢无力及走路不稳。近2年双下肢无力及走路不稳症状明显加重,且双下肢变细伴麻木,双小腿尤其明显,双上肢亦有无力及变细症状,但不明显。患者10年间曾在多家医院就诊,但未能明确诊断。否认有家族史及糖尿病、类风湿性关节炎等病史,无手术及外伤史。体格检查:体温36.6℃,脉搏90次/min,呼吸
Patient, female, 50 years old. Ten years ago, both lower limb weakness and walking instability. In the past two years, both lower extremities weakness and walking instability symptoms were significantly aggravated, and both lower extremities thinner with numbness, especially double calf, upper extremities also have weakness and thinning symptoms, but not obvious. In 10 years, he has been in many hospitals, but he failed to confirm the diagnosis. Denied a family history and diabetes, rheumatoid arthritis and other medical history, no history of surgery and trauma. Physical examination: body temperature 36.6 ℃, pulse 90 beats / min, breathing