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99例肺心病呼衰患者血清乳酸脱氢酶及其同工酶的变化为:①LD_1>LD_2和/或LD_1升高88例(88.89％),LD_1显著高于正常的1.02～3.69倍;②LD_5>LD_4和/或LD_5升高75例(75.76％),LD_5显著升高者55例,平均为正常的6.22±10.51倍,LD_1>10％者23例;③LD_5与LD_1变化呈一定相关关系(r=0.454,P<0.001),肺性脑病时,r=0.62,P<0.001;④4例危重患者LD_5阴极例出现一异常区带。结合临床初步分析了肺心病呼衰时心肌和肝脏急性受损的可能原因。
The changes of serum lactate dehydrogenase (LDH) and its isoenzymes in 99 patients with CPHD were as follows: (1) LD_1> LD_2 and / or LD_1 increased in 88 cases (88.89%), LD_1 was significantly higher than the normal 1.02 ~ 3.69 times; ②LD_5> There were 75 cases (75.76%) in which LD_4 and / or LD_5 increased, 55 cases were significantly elevated in LD_5 (average 6.22 ± 10.51 times, LD_1> 10%); ③LD_5 was correlated with LD_1 (r = 0.454, P <0.001), and pulmonary encephalopathy, r = 0.62, P <0.001. ④Among the four LDH patients, an abnormal zone appeared. Combined with clinical preliminary analysis of pulmonary heart disease respiratory failure during acute myocardial injury and possible causes.