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本文报道2例腺癌患者癌细胞有活跃的吞噬血细胞现象。吞噬的血细胞主要为红细胞,其次为血小板、淋巴细胞、中性粒细胞,一个癌细胞最多吞噬25个红细胞,有的只吞噬一个血细胞。吞噬的血细胞明显变小,模糊,吞噬后癌细胞的核常被掩盖或挤向一侧,有的核呈溶解状,仍将血细胞里着。偶见癌细胞互相吞噬像。光镜下,吞噬现象似呈阿米巴状运动。提示腺癌细胞有活跃的吞噬血细胞现象。对这种吞噬机理,临床意义结合文献复习进行讨论,认为这种吞噬现象与癌患者贫血和免疫功能低下,可能有因果关系。如出现癌细胞吞噬血细胞,似乎预示癌患者已届晚期的一种危象。
This article reports 2 cases of adenocarcinoma cancer cells have active phagocytic phenomenon. Phagocytic blood cells are mainly red blood cells, followed by platelets, lymphocytes, neutrophils, a cancer cells up to 25 red blood cells phagocytosis, and some only swallowed a blood cell. Phagocytic blood cells significantly smaller, blurred, phagocytic cancer cells often covered or squeezed to the side of the nucleus, and some were dissolved nuclei, the blood cells will still be. Occasionally cancer cells engulf each other like. Light microscope, phagocytosis appears to be amoeba-like movement. Tip adenocarcinoma cells have active phagocytosis phenomenon. This phagocytosis mechanism, clinical significance and literature review to discuss that this phagocytosis and cancer patients with anemia and immune dysfunction, may have a causal relationship. In the event of cancer cells engulfing blood cells, it seems to indicate that the cancer patients have been a late crisis.