论文部分内容阅读
目的:观察急性冠状动脉综合征患者血清单核细胞趋化蛋白-1水平及其临床意义。方法:应用酶联免疫吸附法分别检测急性心肌梗死(n=30)、不稳定性心绞痛(n=30),稳定性心绞痛(n=30)及对照组(n=30)患者血清单核细胞趋化蛋白-1水平,并进行比较。结果:急性心肌梗死组血清单核细胞趋化蛋白-1水平高于稳定性心绞痛组和对照组,差异有统计学意义(P<0.05),而稳定性心绞痛组与对照组之间血清单核细胞趋化蛋白-1差异无统计学意义(P>0.05)。结论:急性冠状动脉综合征患者血清单核细胞趋化蛋白-1水平明显增高,是斑块不稳定性的标志之一。
Objective: To observe the serum level of monocyte chemoattractant protein-1 in patients with acute coronary syndrome and its clinical significance. Methods: The levels of serum monocytes in patients with acute myocardial infarction (n = 30), unstable angina pectoris (n = 30), stable angina pectoris (n = 30) and control group (n = 30) were detected by enzyme linked immunosorbent assay Chemotactic protein-1 levels were compared and compared. Results: The level of serum monocyte chemoattractant protein-1 in acute myocardial infarction group was significantly higher than that in stable angina pectoris group and control group (P <0.05), while the levels of serum mononuclear cell in stable angina pectoris group and control group There was no difference in chemotactic protein-1 (P> 0.05). Conclusion: The serum level of MCP-1 is significantly increased in patients with acute coronary syndrome, which is one of the markers of plaque instability.