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目的:分析对一例烟雾病患者进行药物治疗的合理性。方法 :对我院收治的1例烟雾病患者的临床资料进行回顾性分析,探讨对其进行药物治疗,尤其是使用抗菌药物及治疗神经系统疾病的药物对其进行治疗的合理性。结果 :本研究中的一例烟雾病患者发生了脑缺血,进行保守治疗的效果不好,故为其施行外科手术治疗。为该患者进行手术治疗的时间为4h,手术过程较顺利,术中的出血量约为100ml。该患者在进行术后抗炎、营养神经及清除自由基等药物治疗后其手术切口愈合良好,经复查头颅CT显示其脑梗塞得到改善,病情好转出院。我院医师为该患者使用抗菌药物进行治疗的方案缺少相应的理论依据,为其联合使用美洛培南和丙戊酸钠的方案不合理,其他用药的方案基本合理。结论 :为烟雾病患者联合使用美洛培南和丙戊酸钠进行治疗属于不合理用药。在对烟雾病患者进行药物治疗期间,应全面考虑为其选用药物的种类、联合用药的配伍禁忌及导致不良反应的情况,搜集明确的用药依据,以避免发生不合理用药的情况。
OBJECTIVE: To analyze the rationality of drug treatment in a patient with moyamoya disease. Methods: A retrospective analysis was performed on the clinical data of one patient with moyamoya disease admitted to our hospital to investigate the rationality of its treatment with drugs, especially antibiotics and drugs for treating nervous system diseases. Results: In this study, one patient with moyamoya disease developed cerebral ischemia, and the conservative treatment was not effective, so it was treated by surgery. Surgical treatment for the patient’s time was 4h, the operation was smoother, the amount of bleeding during surgery was about 100ml. After the patient had anti-inflammatory, nutritional nerve and free radical scavenging, the surgical incision healed well. After reviewing the head CT, the cerebral infarction was improved and the patient’s condition improved and discharged. Our hospital physicians for the treatment of patients with antimicrobial drugs lack the appropriate theoretical basis for the program for its joint use of meropenem and sodium valproate regimens unreasonable, and other drug programs are reasonable. Conclusion: The combination of meropenem and sodium valproate for patients with moyamoya disease is irrational. In the treatment of patients with moyamoya disease should take full account of the types of drugs for their selection, combined drug incompatibility contraindications and lead to adverse reactions to collect a clear basis for the use of drugs to avoid irrational use of drugs.