Non-peptidyl low molecular weight radical scavenger IAC attenuates DSS-induced colitis in rats

• 作 者: Valentina Vasina Massimiliano
• 机 构: DepartmentofPharmacologyUniversityofBologna,DepartmentofOrganicChemistry',A.Mangini',,Medestea
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2010年29期
• 基金项目: Supported by A Grant from the University of Bologna (Ricerca Fondamentale Orientata)

AIM:To investigate the effects of the free radical scavenger bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl) decandioate(IAC) in the dextran sodium sulphate(DSS) experimental model of ulcerative colitis.METHODS:Colitis was induced in Sprague Dawley male