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目的探讨在慢性肝病发生胆囊结石的发生规律、影响因素及可能机制。方法采用B型超声波观察、比较慢性肝炎、肝硬化,胆囊结石发生的情况差异。结果胆囊结石的发生率,慢性肝病组高于对照组(P<0.05);而慢性肝炎组低于肝硬化组(P<0.05)。虽然胆结石的发生率在慢性肝病组及对照组均有随年龄增长而升高的趋势,但慢性肝病可使胆结石的发生趋向年轻化。结论慢性肝病患者是胆结石的高发人群。患者的肝病病程长短、年龄及肝功受扣程度可影响慢性肝痛合并胆结石的发生率。“,”To study the incidence, causing factors and possible mechanismsof chronic hepatitis complicated with gallstones. Methods Ultrasonic B was applied to observe and contrast the differences in chronic hepatitis and liver cir rhosis complicated with gallstones. Results The incidence of gallstones in patients with chronic hepatitis was higher than that in the control group (P< 0.05), while the incidence of gallstones in chronic hepatitis was lower than that in liver cirrhosis (P< 0.05). The incidence of gallstones was increased with aging but tended to occur in younger group. Conclusion The prevalence of gallstones was higher in patients with chronic hepatitis and liver cirrhosis, and the incidence may be associated with the duration of the liver disease, and the age of the patients as well as the severity of the damage to liver functions.