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目的:探讨肾移植术后医院尿路感染的病原菌谱及其危险因素和危险期。方法:定期监测 76 例肾移植患者术后尿液的病原菌情况,统计多种因素与尿路感染的病原菌谱和发生率的关系。结果:76 例患者发生尿路感染30 例,发生率为39.5% 。分离出真菌 16 株(35.6% ),肠杆菌科菌14 株(31.1% ),其他菌 15 株(33.3% )。术后 5~17 d 感染者24 例,占感染总数的80.0% 。结论:肾移植术后5~17 d 是医院尿路感染的危险期。病原菌以真菌、肠杆菌科菌为主。急性排斥反应及其治疗、留置导尿管、广谱抗生素的应用等是影响病原菌谱及发生率的主要因素。
Objective: To investigate the pathogenic bacteria spectrum of urinary tract infection and its risk factors and dangerous period in hospital after renal transplantation. Methods: The pathogen of urine in 76 renal transplant recipients was monitored on a regular basis. The relationship between pathogens and incidence of urinary tract infection was analyzed. Results: Thirty urinary tract infections occurred in 76 patients, the incidence rate was 39.5%. 16 fungi (35.6%), 14 (31.1%) Enterobacteriaceae and 15 (33.3%) other fungi were isolated. In 5 to 17 days after operation, 24 cases were infected, accounting for 80.0% of the total number of infections. Conclusions: The risk of urinary tract infection in hospital is 5 to 17 days after renal transplantation. Pathogenic fungi, Enterobacteriaceae-based. Acute rejection and its treatment, indwelling catheter, the application of broad-spectrum antibiotics are the main factors affecting the spectrum and incidence of pathogenic bacteria.