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目的了解2008年医院小儿腹泻病病原体的分布及感染情况。方法菌株鉴定采用法国生物梅里埃公司的VITEK60分析仪,药敏试验采用K-B法,轮状病毒监测采用北京万泰生物药业股份有限公司生产的轮状病毒试剂盒。结果轮状病毒是引起腹泻的主要病原体,占83.2%;其次为真菌,占11.7%;再次为志贺菌属和沙门菌属各占2.5%和1.7%。结论 2008年检出的病原体中未发现霍乱弧菌,轮状病毒感染是引起婴幼儿腹泻主要原因之一,开发应用安全有效的轮状病毒疫苗对减轻轮状病毒疾病负担有重要作用。
Objective To understand the distribution and infection of pathogens in pediatric diarrhea in hospitals in 2008. Methods The strain was identified by the VITEK60 analyzer of BioMerieux France, K-B method was used for drug sensitivity test, and rotavirus kit produced by Beijing WANT Bio-medicine Co., Ltd. was used for monitoring rotavirus. Results Rotavirus was the main cause of diarrhea, accounting for 83.2%; followed by fungi, accounting for 11.7%; again for the Shigella and Salmonella 2.5% and 1.7% respectively. Conclusions Vibrio cholerae was not found in the pathogens detected in 2008. Rotavirus infection is one of the major causes of diarrhea in infants and young children. Developing and applying a safe and effective rotavirus vaccine plays an important role in reducing the burden of rotavirus disease.