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激素补充治疗(hormone replacement therapy,HRT)是预防和治疗绝经后女性骨质疏松症(osteoporosis,OP)的一线治疗方案,但是中国女性HRT接受率仅1%~2%,主要原因是担心其不良反应的发生。因此,对于不愿意接受HRT或者有HRT禁忌证的绝经后骨质疏松症女性患者,可以用非激素类药物如选择性雌激素受体调节剂、双膦酸盐、降钙素、甲状旁腺激素、锶盐、维生素K等。
Hormone replacement therapy (HRT) is the first-line treatment for the prevention and treatment of osteoporosis (OP) in postmenopausal women. However, the HRT in Chinese women is only 1% ~ 2% The reaction occurred. Therefore, non-hormone drugs such as selective estrogen receptor modulators, bisphosphonates, calcitonin, and parathyroid can be used in women with postmenopausal osteoporosis who are unwilling to receive or have contraindications to HRT Hormones, strontium salts, vitamin K and so on.