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以口服和注射茶碱处理气道阻塞的患者时,常因感染而需并用抗生素,当两药并用时,红霉素可使血清中茶碱浓度显著升高。作者报道1例并非在上述两药并用期间,而是在停用红霉素后不久,血清茶碱浓度出现意外地升高。病人,男性55岁。系慢性支气管炎的吸烟者,体重75kg。因严重气道阻塞而住院。测得血清茶碱值为4.5mg/L(入院前服用长效氨茶碱)。仍继续口服茶碱并用支气管扩能剂。因推测有肺部感染而加用红霉
Oral and injection of theophylline in patients with airway obstruction, often due to infection and the need for antibiotics, when used in combination, erythromycin can make the serum theophylline concentration was significantly increased. The authors report that one case did not show an unexpected increase in serum theophylline concentration not long after the two drugs were used, but shortly after erythromycin administration. Patient, male 55 years old. Department of chronic bronchitis smokers, weight 75kg. Hospitalized for obstructive airway obstruction. Measured serum theophylline value of 4.5mg / L (taking long-acting aminophylline before admission). Still continue oral theophylline and bronchodilators. Because of speculation of lung infection plus erythroid