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目的:探讨脑电图检查对新生儿缺氧缺血性脑病早期诊断及预后判断的临床意价值。方法:本研究所选研究对象为我院2011年3月至2014年3月住院的91例出生后一天内的窒息新生儿,对其行脑电图检查,根据脑电图的检查结果将其分为四组,分别为正常组、轻度异常组、中度异常组、重度异常组。对上述四组患儿进行随访,时间点为出生后3个月、6个月,采用婴幼儿发育量表对患儿的智能发育进行测评,对各组智能发育的差异进行比较。结果:(1)91例患儿中,脑电图异常的有83例,异常率为91.21%,脑电图的异常程度与临床分度基本一致;(2)对患儿随访至3个月时,轻度、中度、重度异常组患儿的智力发育指数与运动发育指数的平均值与正常组患儿相比,具有显著差异(P<0.05);(3)对患儿随访至6个月时,轻度异常组患儿的智力发育指数与运动发育指数的平均值与正常组患儿相比,无显著差异(P>0.05)。中度、重度异常组患儿的智力发育指数与运动发育指数的平均值与正常组患儿相比,具有显著差异(P<0.05)。结论:早期脑电图检查结果对新生儿缺氧缺血性脑病的早期诊断有利,为临床上早期干预提供了重要的参考依据。
Objective: To investigate the value of EEG in the early diagnosis and prognosis of neonatal hypoxic-ischemic encephalopathy. Methods: The subjects selected in this study were 91 asphyxiated newborns who were hospitalized from March 2011 to March 2014 in our hospital. The neonates were subjected to EEG examination. According to the results of EEG examination, Divided into four groups, namely normal group, mild abnormal group, moderate abnormal group, severe abnormal group. The above four groups of children were followed up for 3 months and 6 months after birth. The intelligence development of the children was evaluated by using Infant Development Scale. The differences of intelligence development in each group were compared. Results: (1) There were 83 cases of abnormal EEG in 91 children, the abnormal rate was 91.21%. The abnormality of EEG was consistent with the clinical index; (2) The follow-up of children to 3 months (P <0.05). (3) The average follow-up of children with mild to moderate and severe abnormalities was significantly higher than that of normal children There was no significant difference (P> 0.05) between the average value of mental development index and motor development index of children with mild abnormality at the age of 1 months. The mean value of mental development index and motor development index of children with moderate and severe abnormalities was significantly higher than that of normal children (P <0.05). Conclusion: The result of early EEG is beneficial to the early diagnosis of neonatal hypoxic-ischemic encephalopathy, which provides an important reference for clinical early intervention.