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本文利用中药R对食管癌高发区辉县居民进行随机双盲干预治疗研究。干预治疗1年，组织学检查显示：食管上度增生情况好转，但与安慰剂组相比未见差异（P＞0．05）。R治疗组3H-TdR标记率（O．0319）与安慰剂组标记率（0．0293）相比也未见差异（P＞0．05）。这可能是因为：①干预治疗以及随访时间不够长，未能显示出有意义的效应；②给药量不足；③机体代谢或各种因素之间的相互影响。
In this paper, Chinese medicine R is used to randomize double-blind treatment for residents of Huixian County, who has a high incidence of esophageal cancer. One year after intervention therapy, histological examination showed that the degree of hyperplasia of the esophagus improved, but there was no difference compared with the placebo group (P>0.05). The 3H-TdR labeling rate (O.0319) in the R-treated group was not different from that in the placebo group (0.0293) (P>0.05). This may be because: 1 intervention therapy and follow-up time is not long enough, failed to show a meaningful effect; 2 lack of dose; 3 the body’s metabolism or interaction between various factors.