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将45例盆腔及腹部肿瘤患者分3组进行治疗,单纯放疗组15例,单纯热疗组14例,放疗+热疗16例。治疗前及结束时分别采取外周静脉血,用直接免疫荧光-流式细胞仪技术测定淋巴细胞CD3、CD4、CD8、CD56、CD25、CD80抗原的阳性率。探讨放疗、热疗对盆腔腹部肿瘤患者细胞免疫功能的影响。结果:治疗后单纯放疗组CD3、CD56、CD25、CD80阳性率和CD4/CD8比值明显下降,而在单纯热疗组则明显上升,在放疗加热疗组治疗前后无明显变化。提示局部热疗可刺激机体免疫功能。
Forty-five patients with pelvic and abdominal tumors were divided into three groups. Fifteen patients in the radiotherapy alone group, 14 in the hyperthermia group and 16 in the radiotherapy plus hyperthermia group. Peripheral venous blood was taken before and at the end of treatment, and the positive rate of CD3, CD4, CD8, CD56, CD25 and CD80 antigen in lymphocytes was measured by direct immunofluorescence-flow cytometry. To investigate the effects of radiotherapy and hyperthermia on cellular immune function in patients with pelvic abdominal tumor. Results: After treatment, the positive rate of CD3, CD56, CD25 and CD80 and the ratio of CD4 / CD8 in radiotherapy group decreased significantly, but in hyperthermia group, they were significantly increased. There was no significant difference between radiotherapy and thermotherapy group before and after treatment. Tip hyperthermia can stimulate the body’s immune function.