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目的通过对江苏省2005年-2013年脊髓灰质炎(脊灰)实验室网络监测数据进行分析,评估其运转情况,为江苏省继续维持无脊灰状态提供病毒学数据。方法分析全省13个地级市上报的急性弛缓性麻痹(AFP)病例个案送检表、江苏省脊灰实验室病原学监测数据和国家脊灰实验室对所有脊灰病毒株进行型内鉴定数据库。结果 2005年-2013年江苏省脊灰实验室共收到2 413例AFP病例粪便标本,252例AFP病例接触者粪便标本,检测未发现脊灰野病毒和疫苗衍生脊灰病毒(VDPV)。脊灰实验室每年均通过了世界卫生组织(WHO)和国家脊灰实验室盲样标本的能力验证和现场认证评估,细胞系敏感性也均达到WHO的要求。结论江苏省脊灰实验室网络运转良好,细胞系是敏感、有效的,为江苏省继续保持无脊灰状态提供了实验室依据。
Objective To analyze the monitoring data of poliomyelitis (polio) laboratory network in Jiangsu Province from 2005 to 2013 to evaluate its operation and provide virological data for the continued maintenance of polio-free status in Jiangsu Province. Methods The cases of acute flaccid paralysis (AFP) reported by 13 prefecture-level cities in the province were analyzed. The results showed that all the poliovirus strains were identified by the poliovirus laboratory in Jiangsu Province database. Results A total of 2 413 stool samples of AFP cases and 252 stool samples of AFP cases were collected from the polio laboratory of Jiangsu Province during 2005-2013. No poliovirus or vaccine-derived poliovirus (VDPV) was detected. Each year, the polio laboratory has passed the capacity verification and on-site certification assessment of blind samples from the World Health Organization (WHO) and the National Polio Laboratory, and the cell line sensitivity has also met the WHO requirements. Conclusion The network of the polio laboratory in Jiangsu Province is working well. The cell lines are sensitive and effective, providing a laboratory basis for maintaining polio-free status in Jiangsu Province.