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目的分析降钙素原及超敏C反应蛋白在新生儿败血症初期的变化特点。方法选取医院收治的新生儿败血症患儿32例作为观察组,另选取32例非感染性疾病患儿为对照组,2组患儿分别进行降钙素原及超敏C反应蛋白检测,比较其结果并分析降钙素原及超敏C反应蛋白检测指标的敏感性、特异性与准确度。结果降钙素原及超敏C反应蛋白,观察组均高于对照组(P<0.05);2种检测指标的敏感性、特异性与准确度比较,降钙素原高于超敏C反应蛋白(P<0.05)。结论降钙素原及超敏C反应蛋白在新生儿败血症早期诊断中具有较高的临床价值,敏感性、特异性与准确度高,值得推广应用。
Objective To analyze the changes of procalcitonin and high sensitivity C-reactive protein in the early stage of neonatal septicemia. Methods Thirty-two neonates with sepsis were selected as the observation group and 32 children with non-infectious disease were selected as the control group. The levels of procalcitonin and hypersensitive C-reactive protein were detected in two groups, respectively Results The sensitivity, specificity and accuracy of procalcitonin and hypersensitive C-reactive protein test were analyzed. Results The levels of procalcitonin and hypersensitive C-reactive protein in the observation group were significantly higher than those in the control group (P <0.05). The sensitivity, specificity and accuracy of the two test indexes were higher than those of the hypersensitive C reaction Protein (P <0.05). Conclusions Procalcitonin and hypersensitive C-reactive protein have high clinical value in the early diagnosis of neonatal septicemia, and their sensitivity, specificity and accuracy are high and worthy of popularization and application.