论文部分内容阅读
甲硝唑是一种抗厌氧菌药物,笔者1989～1990年内遇5例患者在使用甲硝唑疗程中出现毒性反应症状,报告如下: 例1:张某,男,69岁。患胆系结石10余年,右上腹不适及疼痛2天于1989年8月12日入院。体温37.6℃,呼吸平稳,巩膜轻度黄染,脉搏72次/分,血压1′/1,kPa,腹软,右上腹压痛(±),B超提示胆囊总胆管结石,总胆管轻度扩张>1cm,BUN5.712mmol/L,Cr106.08μmol/L,GPT25U,ⅡⅠ10~u,ZnTT12~u,TTT6~u,入院第三天腹痛加重,体温39℃,WBC18.9×10,/L,N0.90,血压8./4.8kPa,脉搏110次/分,经抗休克后急诊手术,术中见腹膜、大网膜、肠
Metronidazole is an anti-anaerobic drugs, the author encountered in 1989 to 1990, 5 patients in the course of the use of metronidazole toxicity symptoms, the report is as follows: Example 1: Zhang, male, 69 years old. Suffering from gallstones more than 10 years, right upper quadrant discomfort and pain for 2 days in August 12, 1989 admission. Body temperature 37.6 ℃, stable breathing, mild yellowish scleral stained, pulse 72 beats / min, blood pressure 1/1, kPa, abdominal soft, right upper quadrant tenderness (±), B ultrasound prompt gallbladder common bile duct stones, , BUN5.712mmol / L, Cr106.08μmol / L, GPT25U, ⅡⅠ10 ~ u, ZnTT12 ~ u, TTT6 ~ u. On the third day after admission, abdominal pain increased, body temperature 39 ℃, WBC18.9 × 10, .90, blood pressure 8./4. 8kPa, pulse 110 beats / min, after anti-shock emergency surgery, intraoperative see peritoneum, omentum, intestine