论文部分内容阅读
将妊娠28周的受试孕妇随机分为4组,分别1次性口服维生素D(VD)10万IU或肌注VD10万IU或20万IU,对照组口服空白胶囊.结果3个补充组产妇血和脐血25-(OH)D水平以及产妇血钙水平显著高于对照组(P<0.05),而产妇血和脐血25-(OH)D小于27.3nmol/L(11ng/ml)的发生率以及孕后期腿抽筋的发生率显著低于对照组,补充组产妇血25-(OH)D水平高于其妊娠28周时的水平.补充组未发现先天性佝偻病,而对照组先天性佝偻病和可疑先天性佝偻病的发生率显著高于补充组。结果提示孕后期补充VD可明显改善孕妇和胎儿的VD和钙的营养状况.预防先天性佝偻病,品服与肌泣10万IU与20万IU效果相同.
Pregnant women at 28 weeks of gestation were randomly divided into 4 groups: oral administration of 100 000 IU of vitamin D (VD), 100000 IU of intramuscular injection of VDU or 200000 IU of intramuscular injection respectively, and oral blank capsules in the control group.Results Three complementary groups of maternal 25- (OH) D levels in blood and umbilical cord blood and maternal serum calcium levels were significantly higher than those in the control group (P <0.05), whereas 25- (OH) D in maternal and umbilical blood was less than 27.3 nmol / L Incidence and the incidence of post-pregnancy leg cramps was significantly lower than the control group, the supplementary group of maternal blood 25- (OH) D levels higher than its level at 28 weeks of pregnancy. Supplementary group found no congenital rickets, while the control group of congenital The incidence of rickets and suspicious congenital rickets was significantly higher than that of the supplementation group. The results suggest that supplementation of VD during pregnancy can significantly improve the nutritional status of VD and calcium in pregnant women and fetuses.Prevention of congenital rickets, product service and weiqi 100,000 IU and 200,000 IU the same effect.