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本文对11名怀孕三个月左右的妇女、11名服用长效口服避孕药“孕素1号”片的妇女和11名正常妇女的外周血淋巴细胞进行了姐妹染色单体互换的研究。研究结果表明:怀孕妇女和服用避孕药妇女的姐妹染色单体互换平均值与正常妇女相似。服药妇女和正常妇女、怀孕妇女和正常妇女之间的差异均无统计学意义(P>0.05)。提示合成的甾体激素避孕药——复方孕素1号片和怀孕妇女激素变化都不引起淋巴细胞姐妹染色单体互换的增加。
In this paper, we studied the sister chromatid exchange of 11 pregnant women who were about three months pregnant, 11 women who took the long-acting oral contraceptive pill “Gensu No.1” and 11 normal women’s peripheral blood lymphocytes. The results show that pregnant women and women taking contraceptive sisters chromatid interchangeable average with normal women. There was no significant difference between medication women and normal women, pregnant women and normal women (P> 0.05). Tip synthesis of steroid hormonal contraceptives - compound progesterone tablets and pregnant women hormone changes do not cause lymphocyte sister chromatid exchange increased.