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C-fos基因为一段3.5kb的DNA,定位于人类染色体14q21-23,人和鼠C-foS基因具同源性,它的全部核音酸已被克隆并测序[1]。c-fos是一种快速的早期反应基因(Immediatelyearlygene),对生理或药理刺激能在数十分钟内作出表达:C-fos基因被激活,转录形成c-fosm-RNA,随后
The C-fos gene is a 3.5-kb DNA that is located on the human chromosome 14q21-23. The human and murine C-foS genes are homologous and all of their nucleic acids have been cloned and sequenced [1]. c-fos is a rapid early response gene that can be expressed in tens of minutes for physiological or pharmacological stimuli: the C-fos gene is activated, transcribed to form c-fosm-RNA, and subsequently