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在以往的实验中发现 ,分次小剂量放射免疫治疗 (ＲＩＴ)对荷瘤小鼠实验动物模型肿瘤的抑制和控制转移与单次大剂量ＲＩＴ、单纯化疗、手术比较 ,作用更明显。本研究探讨了小剂量ＲＩＴ的抑瘤机制 ,现报道如下。材料与方法1 动物模型。Ｔ739近交系小鼠 ,6～ 8周龄 ,体重 2 2～ 2
In previous experiments, it was found that the fractional low-dose radioimmunotherapy (RIT) significantly inhibited tumor growth and metastasis in tumor-bearing mice compared with single high-dose RIT, chemotherapy alone and surgery. This study explored the low-dose RIT tumor suppressor mechanism, are reported below. Materials and Methods 1 animal model. T739 inbred mice, 6 to 8 weeks old, weighing 2 2 ~ 2