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应用ＥＬＩＳＡ和ＰＣＲ法检测５０２例乙肝病人血清，４０１例ＨＢｓＡｇ阳性血清中，有１１４例（２８．４％）抗－ＨＣＶ和ＨＣＶＲＮＡ双项阳性，２５例（６．２％）ＨＣＶＲＮＡ单项阳性；２１例（５．２％）抗－ＨＣＶ单项阳性。将ＨＢｓＡｇ乙肝病人分成ＨＢＶＤＮＡ，ＨＢｅＡｇ阳性组和ＨＢＶＤＮＡ，ＨＢｅＡｇ阴性组。前者抗－ＨＣＶ阳性率为１１．６％～２０．５％，ＨＣＶＲＮＡ阳性率为１６．２％～２０．５％。后者抗－ＨＣＶ阳性率为２０．２％～５５．６％，ＨＣＶＲＮＡ阳性率为２３％～６０．３％。结果说明长期携带ＨＢＶ者和慢性乙肝病人均可重叠ＨＣＶ感染。ＨＢＶＤＮＡ阳性组抗－ＨＣＶ和ＨＣＶＲＮＡ阳性率明显高于ＨＢＶＤＮＡ阳性组
Serological samples from 502 hepatitis B patients were detected by ELISA and PCR. Of the 401 HBsAg positive sera, 114 (28.4%) were positive for anti-HCV and HCV RNA, and 25 (6.2%) were HCV RNA single positive; Cases (5.2%) anti-HCV single positive. HBsAg hepatitis B patients were divided into HBVDNA, HBeAg-positive group and HBVDNA, HBeAg-negative group. The former anti-HCV positive rate was 11.6% ~ 20.5%, HCVRNA positive rate was 16.2% ~ 20.5%. The latter anti-HCV positive rate was 20.2% ~ 55.6%, HCVRNA positive rate of 23% to 60.3%. The results show that long-term HBV carriers and chronic hepatitis B patients can overlap HCV infection. The positive rates of anti-HCV and HCV RNA in HBVDNA-positive group were significantly higher than those in HBVDNA-positive group