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小儿肾病综合征(简称NS)的治疗从五十年代应用肾上腺皮质类固醇激素(简称激素)以来,已取得飞跃的进展。NS 按原因与组织学所见分为原发性(特发性)NS 与续发性NS 两大类。续发性NS 的治疗主要是针对基础疾病,原发性NS 则主要使用激素。小儿NS 的95%属原发性,而原发性NS 中80%是微小病变型,因此激素是治疗小儿NS 最有效的药物。激素治疗NS 目前常用的为强的松中长程疗法与短程疗法两种。中长程疗法整个疗程约6～8个月,先以强的松1～1.5毫克/公斤/日,分次服用共4周,以后间歇给药维持并渐减
Treatment of pediatric nephrotic syndrome (NS) has made leapfrog progress since the advent of the adrenal corticosteroids (Hormone) in the 1950s. NS according to the reasons and histological findings divided into primary (idiopathic) NS and secondary NS two categories. The treatment of persistent NS is mainly for underlying diseases, while the primary NS is the main use of hormones. Ninety-five percent of children with NS are primary, and 80% of primary NS is a minor lesion, so hormones are the most effective drug for pediatric NS. Hormone therapy NS is currently used for prednisone in the long-term therapy and short-course therapy two. The long-term treatment of the entire course of about 6 to 8 months, the first prednisone 1 ~ 1.5 mg / kg / day, taking a total of 4 weeks, divided into groups to maintain and reduce intermittent