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乙型肝炎病毒(HBV)感染呈世界性流行,但不同地区HBV感染的流行强度差异很大。HBV感染人群罹患肝硬化和肝细胞癌的相对危险至少增加1000倍,并最终导致死亡。核苷(酸)类药物可迅速抑制慢性乙型肝炎(简称乙肝)患者病毒复制,改善患者临床症状和肝功能,肝组织病理学也得到改善,但核苷(酸)类药物的使用在适应症的选择及用药周期上是有严格要求的,治疗时间至少1年,但是有一些患者因各种原因未按要求服药,据报道大约1/3左右的患者存在不正确使用干扰素和拉米夫定这些治疗乙肝的药物。现将临床上2例患者自行
Hepatitis B virus (HBV) infection is worldwide epidemic, but the prevalence of HBV infection in different areas vary greatly in intensity. The relative risk of developing liver cirrhosis and hepatocellular carcinoma in HBV-infected individuals increases by at least a factor of 1000 and eventually leads to death. Nucleoside (acid) drugs can rapidly inhibit the virus replication in patients with chronic hepatitis B (referred to as hepatitis B), improve clinical symptoms and liver function in patients, hepatic histopathology has also been improved, but the use of nucleoside (acid) drugs in adaptation There are strict requirements on the choice and duration of the treatment, and the treatment time is at least 1 year. However, some patients do not take medication as required for various reasons. About one-third of the patients reportedly have incorrect use of interferon and Lamy Fudge these drugs for the treatment of hepatitis B. Now clinically 2 patients on their own