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通过实验动物（成年雄性狗）研究肽能神经介质──降钙素基因相关肽（ＣＧＲＰ）在勃起机制中的作用。取动物海绵体平滑肌、阴部内动脉、静脉等组织离体灌注并活体海绵体内注射ＣＧＲＰ，证实对离体组织具有舒张作用，以海绵体平滑肌最强。活体海绵体内注射观察动脉血流量增加，海绵体内压升高，阴茎明显胀大。刺激海绵体神经诱导阴茎勃起检测ＣＧＲＰ水平变化，发现在勃起高峰时，海绵体组织内ＣＧＲＰ增高，面消退期血浆内ＣＧＲＰ升高。从而证实ＣＧＲＰ可导致海绵体平滑肌松弛、减少阻力，增快动脉血流，是促使阴茎勃起的主要神经介质之一。在消退期也可能参与使阻闭静脉的开放，加快回流的作用。
The role of calcitonin gene-related peptide (CGRP) in the erectile mechanism was investigated in experimental animals (adult male dogs). Sponge smooth muscle, intra-genital artery, vein and other tissues were perfused intraperitoneally and injected intraperitoneally with CGRP. It was found that diastolic function was observed in isolated tissues, with strongest sponge smooth muscle. In vivo sponge injection of arterial blood flow was observed increased intracavernosal pressure, penis was significantly swollen. Stimulation of cavernosal nerve induced penile erection detection of CGRP level changes found in erectile peak, intracavernous tissue CGRP increased in facial hyperplasia CGRP increased. Confirmed that CGRP can lead to spontaneous smooth muscle relaxation, reduce resistance, increase arterial blood flow, is to promote penile erection of one of the main neurotransmitters. In the regression may also be involved in blocking the opening of the vein to speed up the role of reflux.