论文部分内容阅读
目的:探讨采用糖皮质激素加低分子肝素治疗IgA肾病(Ig nephropathy,IgAN)的疗效。方法:选择2006-01/2008-04在本院肾活检诊断为原发性IgAN患者20例,根据病理分级分为A组(Lee氏Ⅰ、Ⅱ级)和B组(Lee氏Ⅲ、Ⅳ级)。用法方法:A组给予法安明(低分子肝素)5 000 IU,皮下注射,同时口服ACEI或ARB类;B组给予口服强的松30~40 mg/d,同时法安明皮下注射,1个月后激素逐渐减量,总疗程0.5~1 a,同时口服ACEI类或ARB类。结果:两组均有不同程度好转。结论:根据患者病理分级及24 h尿蛋白定量的不同及血尿程度的不同而采用不同的治疗方案,均收到了较好的疗效。
Objective: To investigate the effect of glucocorticoid plus low molecular weight heparin in the treatment of IgA nephropathy (IgAN). Methods: Twenty patients with primary IgAN diagnosed by renal biopsy in our hospital from January 2006 to April 2008 were selected and divided into group A (Lee’s grade Ⅰ and Ⅱ) and group B (Lee’s Ⅲ and Ⅳ ). Method of usage: Group A was given Fuming (low molecular weight heparin) 5 000 IU, subcutaneous injection, while oral administration of ACEI or ARB; Group B was given oral prednisone 30 ~ 40 mg / d, Months after the gradual reduction of hormones, the total course of 0.5 ~ 1 a, while oral ACEI class or ARB class. Results: Both groups improved in varying degrees. Conclusion: According to the pathological grading of patients and 24 h urinary protein quantitation and the varying degrees of hematuria with different treatment options, have received a good effect.