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目的研究肺泡灌洗术对尘肺病患者发音频率的影响。方法利用二十五音分析仪,检测42例男性尘肺病患者(实验组)肺泡灌洗术前后的肺部发音,同时选择不施行肺泡灌洗术的50例成年男性尘肺病患者(对照组Ⅰ)和31例既往无生产性粉尘接触史的男性健康人员(对照组Ⅱ)进行对照比较。结果实验组术前和对照组Ⅰ发音频率在商音区的百分比(24.76%、22.40%)均高于对照组Ⅱ(13.23%,P<0.05),而羽音区的百分比(27.38%、27.40%)均低于对照组Ⅱ(38.06%,P<0.05);实验组术后在商音区的百分比(17.14%)低于术前和对照组Ⅰ(24.76%、22.40%,P<0.05),在角音区百分比(22.26%)高于术前和对照组Ⅰ(17.38%、18.00%,P<0.05);实验组术后在徽音区的百分比(18.21%)高于对照组Ⅱ(11.94%,P<0.05),在羽音区的百分比(25.77%)低于对照组Ⅱ(38.06%,P<0.05)。实验组术后动脉血氧分压(76.89±6.44)mmHg与术前(74.02±6.13)mmHg比较,差异有统计学意义(P<0.05)。结论肺泡灌洗术前后尘肺病患者发音频率有变化,其变化特征可作为判断肺泡灌洗术疗效的参考指标。
Objective To study the effect of alveolar lavage on phonological frequency in patients with pneumoconiosis. Methods Fifty-five adult male patients with pneumoconiosis without alveolar lavage (control group) were enrolled in this study. Twenty-five male pneumoconiosis patients (experimental group) Ⅰ) and 31 male health workers who previously had no history of exposure to dust (control group Ⅱ). Results The percentages of phonological frequencies in the experimental group Ⅰ and control group Ⅰ (24.76%, 22.40%) were higher than those in the control group Ⅱ (13.23%, P <0.05), while those in the feather zone (27.38%, 27.40% ) Were lower than those in control group Ⅱ (38.06%, P <0.05). The percentage of patients in experimental group after operation was 17.14% lower than that in control group Ⅰ (24.76%, 22.40%, P <0.05) (22.26%) was higher than preoperative and control group I (17.38%, 18.00%, P <0.05). The percentage of experimental group in Huyin District was 18.21% higher than that in control group Ⅱ (11.94% , P <0.05). The percentage of feather area (25.77%) was lower than that of control group (38.06%, P <0.05). The postoperative arterial partial pressure of oxygen (76.89 ± 6.44) mmHg in the experimental group was significantly lower than that of the preoperative (74.02 ± 6.13) mmHg (P <0.05). Conclusions The frequency of phonation in patients with pneumoconiosis before and after alveolar lavage may vary. The changing characteristics may be used as a reference index to evaluate the efficacy of alveolar lavage.