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目的:观察产妇在分娩过程中应用催产素对新生儿高胆红素血症的影响。方法:选择320例足月健康新生儿,根据孕母产前是否使用催产素分为两组,观察组(使用催产素)108例,对照组(未使用催产素)212例,在出生后分别检测两组新生儿胆红素的水平及高胆红素血症发生率。结果:观察组胆红素的均值(287.73±41.27)μmol/L,明显高于对照组(184.73±62.70)μmol/L(u=17.58,P<0.01),观察组高胆红素血症的发生率为38.89%,高于对照组的25.00%(χ2=6.61,P<0.05),差异均有统计学意义。结论:孕妇分娩时使用催产素可增加新生儿高胆红素血症的发生率,新生儿出生后应及早监测血清胆红素浓度。
Objective: To observe the effects of oxytocin on neonatal hyperbilirubinemia during labor. Methods: A total of 320 full-term healthy newborns were enrolled. According to whether prenatal oxytocin was used or not, 108 cases in the observation group (using oxytocin) and 212 in the control group (without oxytocin) were divided into two groups after birth Neonatal bilirubin levels and hyperbilirubinemia were detected in both groups. Results: The mean bilirubin in the observation group was significantly higher than that in the control group (287.73 ± 41.27 μmol / L, 184.73 ± 62.70 μmol / L, u = 17.58, P <0.01) The incidence was 38.89%, which was higher than 25.00% of the control group (χ2 = 6.61, P <0.05). The differences were statistically significant. Conclusion: The use of oxytocin in pregnant women can increase the incidence of neonatal hyperbilirubinemia, newborns should be monitored as soon as possible after birth bilirubin concentration.