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目的探讨老年男性2型糖尿病患者血小板参数的变化及其临床意义。方法对糖尿病组60例(其中合并血管病变者35例,不伴血管病变者25例)及对照组30例分别检测血小板4项参数,并对结果进行对比分析。结果与对照组比较,糖尿病患者的平均血小板体积(MPV)和血小板分布宽度(PDW)均明显升高(P<0.05);糖尿病伴血管病变者血小板计数(PLT)、血小板压积(PCT)、MPV及PDW较不伴血管病变者更为升高(P<0.01)。结论血小板参数测定为临床诊断和治疗糖尿病提供实验室依据;血小板参数测定对2型糖尿病血管病变的早期诊断和病情分析有临床参考价值。
Objective To investigate the changes of platelet parameters in elderly male patients with type 2 diabetes mellitus and its clinical significance. Methods Sixty-four patients with diabetes mellitus (35 with vascular disease, 25 without vascular disease) and 30 with control group were tested for platelet parameters, and the results were compared. Results Compared with the control group, the mean platelet volume (MPV) and platelet distribution width (PDW) in diabetic patients were significantly increased (P <0.05). The platelet count (PLT), platelet pressure (PCT) MPV and PDW were higher than those without angiopathy (P <0.01). Conclusion The determination of platelet parameters provides a laboratory basis for clinical diagnosis and treatment of diabetes. The determination of platelet parameters has clinical value in the early diagnosis and condition analysis of type 2 diabetic patients with vascular lesions.