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目的:探讨药学监护对于治疗放射性肺炎合并肺部感染的方法、作用及意义。方法:选取我院2011年1月~2013年1月收治的20例放射性肺炎合并肺部感染患者,将其分为观察组和对照组,两组患者一般资料差异无统计学意义(P>0.05),对照组采用常规治疗方法,观察组采用药学监护方案治疗。结果:治疗后观察组总有效为90%,对照组总有效为60%;治疗后观察组KPS评分为(82.28±5.29),对照组KPS评分为(74.62±2.18);治疗后观察组病灶大小为(34.58±3.01)cm2,对照组病灶大小为(45.59±1.25)cm2,两组患者的数据差异具有统计学意义(P<0.05)。结论:临床药师在参与药物治疗中能够充分发挥其药学专业知识的优势,为临床用药提供良好的参考依据,药学监护在临床治疗中具有推广意义。
Objective: To investigate the method, effect and significance of pharmacy care for the treatment of radiation pneumonitis with pulmonary infection. Methods: Twenty cases of patients with radiation pneumonitis complicated with pulmonary infection admitted in our hospital from January 2011 to January 2013 were divided into observation group and control group. There was no significant difference in general data between the two groups (P> 0.05 ), The control group using conventional treatment methods, the observation group using the drug monitoring program treatment. Results: After treatment, the total effective rate was 90% in the observation group and 60% in the control group. The KPS score was (82.28 ± 5.29) in the observation group and (74.62 ± 2.18) in the control group after treatment. The size of the lesions in the observation group (34.58 ± 3.01) cm2, and the size of the control group was (45.59 ± 1.25) cm2. There was statistically significant difference between the two groups (P <0.05). Conclusion: Clinical pharmacists can take full advantage of their expertise in drug treatment and provide a good reference for clinical use. Pharmacological monitoring is of great significance in clinical treatment.