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1 临床资料 1.1 一般资料 我们1993~1998年收治的24例肝硬变并发低钠性脑病患者,男16例,女8例,年龄26~72岁,平均51.2岁。24例均为活动性肝硬变(依据1995年5月北京第5次全国传染病寄生虫病学术会议讨论修订的病毒性肝炎防治方案)。 1.2 诊断依据 ①有水,电解质大量丢失的明显诱因。②肝功能无明显恶化情况下出现精神、神经症状,补钠后症状明显减轻或由昏迷转为清醒。③查血清钠≤120mmol/L。④排除其它引起脑病的因素。 1.3 临床表现 24例患者均有精神,神经症状,昏迷15例,定向力、计算力丧失6例,嗜睡4例,躁动4例,抽搐3例。 1.4 诱发因素 大量利尿12例,大量放腹水4例,呕吐2例,
1 Clinical data 1.1 General Information We admitted from 1993 to 1998, 24 cases of liver cirrhosis with hyponatremia patients, 16 males and 8 females, aged 26 to 72 years, mean 51.2 years. All 24 cases were active cirrhosis (based on the revised program of prevention and treatment of viral hepatitis discussed in the Fifth National Conference on Infectious Diseases and Parasitic Diseases, Beijing, May 1995). 1.2 based on the diagnosis ① water, a significant loss of electrolytes significant incentive. ② no significant deterioration of liver function in the case of mental, neurological symptoms, sodium supplementation significantly reduced symptoms or from a coma to awake. ③ check serum sodium ≤ 120mmol / L. ④ exclude other etiological factors. Clinical manifestations of 24 patients had mental, neurological symptoms, coma in 15 cases, directional force, loss of calculated power in 6 cases, drowsiness in 4 cases, 4 cases of agitation, convulsions in 3 cases. 1.4 induced a large number of diuresis in 12 cases, a large number of ascites in 4 cases, vomiting in 2 cases,