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作者把34名儿童分为两组。A组儿童18名,服用四次液体脊髓灰质炎(脊灰)三价活疫苗,疫苗直接滴入口腔中,在服苗后一小时内不吃食物和饮水。B组儿童16名,三次吞服脊灰三价活疫苗胶囊,第四次服苗采用A组服用方法。三价活疫苗一个服用剂量配比:Ⅰ型为100～150万空斑形成单位(PFU);Ⅱ型10～25万PFU;Ⅲ型14～30万PFU。第一次服苗时,儿童为2～4个月龄,每次间隔6～8周。用通常方法进行病毒分离和中和抗体测定。粪便标本Ⅰ型病毒分离率,A组和B组儿童,第一次服苗后高(94％和100％),第二次服苗后低(28％和12％),第三次服苗后又增高(25％和56％),第四次服苗后又降低
The author divides 34 children into two groups. A group of 18 children, taking four liquid polio (polio) trivalent live vaccine, the vaccine directly into the oral cavity, within one hour after taking the vaccine do not eat food and water. Group B 16 children, three times swallowing polio vaccine triple live, the fourth service taking group A taking method. Trivalent live vaccine dose ratio: Ⅰ type of 100 to 1.5 million plaque forming units (PFU); Ⅱ 10 to 25 million PFU; Ⅲ type 14 to 300,000 PFU. The first dose of clothing, children 2 to 4 months old, each interval of 6 to 8 weeks. Virus isolation and neutralizing antibody assays were performed in the usual manner. The rate of isolation of type I virus in stool specimens was higher in children in groups A and B than in girls in group A and group B (94% and 100%, respectively), low after the second service (28% and 12%), After the increase (25% and 56%), the fourth service and then reduced